Methotrexate affects the growth of certain cells in the body, especially fast-growing cells such as cancer cells, bone marrow cells and skin cells. The drug is used to treat certain types of breast cancer, skin, head and neck or lung cancer. It is also used to treat severe psoriasis and rheumatoid arthritis.
Take methotrexate exactly as it was prescribed for you. Use it with the glass of water, with or without meals. Avoid chewing and crushing. Usually, the 7.5 mg dose of methotrexate is taken once a week, or 2.5 mg of the drug is taken in three doses every twelve hours, but also once a week. For the treatment of cancer the dosage must be individual.
Be careful using the medication if you have hydroperitonine, dehydration, problems with the digestive tract and kidneys, signs of infection, shingles, chicken pox, allergic reaction, gout, stomach ulcers , a disgust, nausea. Use birth control pills to prevent pregnancy while you are using methotrexate, whether you are a man or a woman. Avoid exposure to the sun.
Do not use this medicine if you are allergic to methotrexate. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have liver or kidney disease or bone marrow disorder. Avoid using the medicine if you have a blood cell abnormality or are breastfeeding a baby.
Possible side effects
The drug can cause side effects that are not usual. Sometimes this can be leukopenia, problems with the belly, liver, kidneys, lungs and bone marrow disorders, nausea, vomiting, fatigue, headaches, allergies, rashes and hair loss.
Before taking methotrexate, tell your doctor if you are taking any other medicines, including ibuprofen, diclofenac, naproxen, indomethacin, azathioprine, gout medicines, chloramphenicol, hydroxychloroquine, isotretinoin, steroids, sulfonamides, probenecid, tetracycline, diabetes medications or penicillin.
Tell your doctor if you have missed a dose of methotrexate.
Seek emergency medical help if you think you have used too much medicine. Symptoms of overdose may include sickness, nausea, bleeding, asthenia, anuria or coughing up of blood.
Store the drug at room temperature between 15-30 C (59-86 F). Keep it away from moisture and light. Keep it out of reach of children and away from pets.
The information presented on the site is of a general nature. Please note that this information can not be used for self-treatment and self-diagnosis. You should consult with your doctor or health advisor regarding any specific instructions for your condition. The information is reliable, but we admit that it may contain errors. We are not responsible for any direct, indirect, special, or consequential damages from others as a result of any use of the information on this site as well as consequences of self-treatment.
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